How To Use A HoMedics Humidifier? A Step-By-Step Guide

HoMedics totalcomfort humidifiers have gained a lot of popularities in recent years. You will be happy with these tiny gadgets. Once you get the device, you may wonder how to use it. 

Luckily, using a HoMedics humidifier is very straightforward. Without further ado. Let’s follow this guide, and you will understand how to operate your lovely HoMedics humidifier within one or two minutes.

Set up HoMedics humidifiers

Before running the HoMedics humidifier, some preparations are required.

Step 1: Decide the placement of your Totalcomfort humidifier

Humidifier placement is important. It decides not only the effect of your humidifier but also the safety of you, your children, and your pets.

It is not advisable to place it on the floor or nightstand or too close to electronics. If you want to use it for your household plants, there are other placement considerations

Step 2: Fill the water tank with clean water

Even though there are various models, most HoMedics humidifiers’ water tanks can be taken out by lifting them from the base. 

Then you need to remove the tank cap and fill the tank with clean water. While it comes with a demineralization cartridge, you’d better add distilled water, especially when the water in your region is relatively hard

Once the tank is full, replace the tank cap and put it back on the base. 

Step 3: Plug it in 

Ensure the power cord and surface of the machine is dry before plugging it in. 

Run HoMedics humidifiers

Many HoMedics humidifiers come with several advanced features, including humidistat, cool/warm mist mode, and night light. You should learn how to adjust these settings.

Step 1: Adjust output rate

homedics humidifier output

Once the device is plugged in, you can press the power button to turn it on. Then you need to set the mist output rate. The higher the output rate, the more mist you can see per unit time. 

If you want your HoMedics humidifier to take less time to work, press the “MIST+” button to increase the output rate. On the contrary, you can press the “MIST-” button to decrease it.

Step 2: Choose the mist temperature model

homedics humidifier mist temperature

Some HoMedics humidifiers can release cool and warm mist, like the HoMedics totalcomfort deluxe one I have.

You can press the mist temperature setting button to choose the mode you prefer, and the default setting is cool mist. 

Note that it will take 20 minutes for the device to heat up the water, so you will not see anything during this period. 

Step 3: Set up the humidistat

homedics humidistat

The indoor humidity that is too high or too low is not ideal. For example, 70% RH can wreak havoc in your house.

Humidistat is a helpful feature to help you regulate the humidity level automatically that you can find in many HoMedics models.

The default setting is “CO,” which means the device will continue to work regardless of humidity. You can press the “Humidistat+” button to increase the targeted humidity level from 35% to 55% with 5% increments. Likewise, you can press the “Humidistat-” to decrease humidity. 

The device will turn off when the targeted level is reached and turn on again when the humidity level drops 5% below the set level.

Step 4: Turn on the nightlight

homedics humidifier nightlight

You can use the “bulb” button to set up the nightlight and display light. When you press it the first time, both the nightlight and display light will turn on. When you keep pressing it, the lights will turn off one by one and then turn on altogether again. 

Step 5: Set the run time

homedics humidifier timer

My HoMedics humidifier can run up to 65 hours per fill. But it is better to turn it off a while every day. Anyway, you have to change out the water daily. 

As for the timer, you can set it from 0 to 24 hours with 2-hour increments. It is useful when you want to run it for your pets or your plants when you are out of the room.

Step 5: Refill the tank again 

Homedics humidifiers will turn off automatically with a red light on when it runs out of water. In this case, you need to press the power button again, pull out the plug, rinse off the tank and refill it with distilled water.

Maintain a HoMedics humidifier

When thinking about using a HoMedics humidifier, you shouldn’t only consider how to run the machine. Maintaining it is also critical. 

Step 1: Routine cleaning 

It may be tedious, but cleaning a HoMedics humidifier regularly is what you have to do. You have to rinse off the tank and reservoir and refill the tank every day, as I mentioned above.

Every three days or week, you can use a solution of white vinegar and lukewarm water with a 1-to-1 ratio to dissolve the slime and scale. 

It is also essential to clean the ultrasonic membrane carefully as it decides if the mist can produce mist normally. 

Step 2: Fix problems

While HoMedics humidifiers are of high quality, they can stop working at some point. If it produces a reduced mist, you may need to give the machine a thoroughly clean. If it makes noise, the surface it is placed on may not be flat. You see, many issues can be solved quickly. You don’t have to seek professional help.


This guide illustrates how to use a HoMedics humidifier correctly. Until now, I think you already have a firm understanding of it. 

In short, after filling the water tank with clean water, you can turn on the machine, and adjust the output rate, mist temperature, humidistat, and timer, then the humidifier will work as you expect. 

Don’t forget to clean the machine frequently to maintain your device in a good state. 

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Liz Yang is the founder of Airsmartly. She has been working at home for a few years and realizes that the performance of the HVAC system plays such an important role in our life. She has tested a lot of products in person, like humidifiers, air purifiers, dehumidifiers, and ACs, and wants to share tips about using or troubleshooting these products with you. Her uncle is an HVAC expert with over 30 years of experience in the field, and often offers assistance when she is unsure how to handle a situation. He is also in charge of reviewing the articles on this site.

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